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Old Apr 26, 2014, 08:23 PM
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Marshellette Marshellette is offline
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I've gathered from research and from doctors telling me that it's not a good idea to give young women Depakote because of the risk of polycystic ovarian syndrome which will happen to 1 in 10 young women on Depakote. Yet I am on 750mg of Depakote. I have heard polycystic ovarian syndrome may or may not be reversible according to hormones because Depakote cuts the connection between progesterone release to the ovaries, making your ovaries store up eggs without releasing them until the ovaries eventually burst. Has this syndrome happened to anyone on here? I stew over it and worry about it every night, in constant terror thinking I could be the one in ten who could get these egg filled sacs that could burst my ovaries and make it so I could never have kids. Making me infertile at 27 when I've never really had the chance to have a family or a life really.
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  #2  
Old Apr 26, 2014, 08:31 PM
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TheatreKid TheatreKid is offline
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Do 1 in 10 women really have burst ovaries from depakote? I think if the stats were really that high, we'd hear about it more.

What do doctors say about this 1 in 10? They've had a lot more specialized schooling than some of us, and it's always your choice in the end. Every med has its risks. I'm a little skeptical about this 1 in 10 burst ovaries though. That sounds too serious.
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  #3  
Old Apr 26, 2014, 08:33 PM
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Marshellette Marshellette is offline
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Quote:
Originally Posted by TheatreKid View Post
Do 1 in 10 women really have burst ovaries from depakote? I think if the stats were really that high, we'd hear about it more.

What do doctors say about this 1 in 10? They've had a lot more specialized schooling than some of us, and it's always your choice in the end. Every med has its risks. I'm a little skeptical about this 1 in 10 burst ovaries though. That sounds too serious.
But if you are a transgender female as your profile says then you will be removing your ovaries so would you really know?
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  #4  
Old Apr 26, 2014, 08:34 PM
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Marshellette Marshellette is offline
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Quote:
Originally Posted by TheatreKid View Post
Do 1 in 10 women really have burst ovaries from depakote? I think if the stats were really that high, we'd hear about it more.

What do doctors say about this 1 in 10? They've had a lot more specialized schooling than some of us, and it's always your choice in the end. Every med has its risks. I'm a little skeptical about this 1 in 10 burst ovaries though. That sounds too serious.
1 in 10 don't get burst ovaries, 1 in 10 get PCOS.
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Old Apr 26, 2014, 08:40 PM
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Thanks for clearing that up.

As a transgender male, I may decide to remove my ovaries. I may not. I don't need ovaries to think critically.

Good luck with the meds, if you decide to go off Depakote I hope you can find a good replacement.
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  #6  
Old Apr 26, 2014, 09:24 PM
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Marshellette Marshellette is offline
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Quote:
Originally Posted by TheatreKid View Post
Thanks for clearing that up.

As a transgender male, I may decide to remove my ovaries. I may not. I don't need ovaries to think critically.

Good luck with the meds, if you decide to go off Depakote I hope you can find a good replacement.
Thank you. I would consider the sex change carefully. You could get messed up by altering the hormones of your natural state.
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  #7  
Old Apr 26, 2014, 09:32 PM
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Nammu Nammu is offline
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I had one and a half of the other ovaries removed due to this, but I already had my daughter before I was diagnosed and had no desire for more kids after I was diagnosed. I was 28 when I was diagnosed.
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  #8  
Old Apr 26, 2014, 11:51 PM
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Marshellette Marshellette is offline
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Originally Posted by sidestepper View Post
I had one and a half of the other ovaries removed due to this, but I already had my daughter before I was diagnosed and had no desire for more kids after I was diagnosed. I was 28 when I was diagnosed.
That's comforting.
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  #9  
Old Apr 27, 2014, 12:08 AM
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Hmm...all I can contribute to this thread is that I was on Depakote years ago for about 2 years. I found it an effective mood stabilizer and I had no problems with POS. It did cause me to gain a lot of weight.
  #10  
Old Apr 28, 2014, 10:13 AM
StartingFreshNow StartingFreshNow is offline
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I have PCOS (prior to going on Depakote).

The only thing I've had happen is I've had a CYST burst - my ovary was completely fine. It hurt like a son of a gun - crippling pain - like I was in labor - but it was just the cyst that burst, not the actual ovary.

As others have said, PCOS does not mean you'll lose an ovary.
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  #11  
Old Apr 28, 2014, 01:26 PM
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ibex ibex is offline
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I had PCOS from Depakote and like StartingFreshNow, one of the cysts burst and it was extremely painful to the point that I doubled over in pain from it. The ovary was fine. There was hemorrhaging showing up on the sonogram that was all we could tell that was going on and the other cysts. I was not made aware that it would endanger my fertility at all. Just a very unpleasant side effect.

I took a break from Depakote for a few years and have been back on again on it for a couple of more years (1000mg a day) and have not had that problem again. Maybe because I am older. Who knows but I am not afraid of it.
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Last edited by ibex; Apr 28, 2014 at 01:42 PM. Reason: spelling
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