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  #1  
Old Oct 12, 2014, 09:35 PM
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sideblinded sideblinded is offline
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I have been on Mirtazapine 15 mg for about 2 months without any problems.....until my pdoc upped my dosage to 30 mg and I became hypomanic in a week. I do not have a mood disorder any other time not on anti-depressants. This happened to me 18 years ago on a similar anti-depressant. I have now noticed that I get anti-depressant induced mania.

The other antidepressant was Doxepin. It is an older generation tricyclic AD. Mirtazapine is a tetracyclic antidepressant and they are similar except for a slight difference in their chemical makeup.

Has anyone else had this type of experience?

MDD
GAD
ADHD?

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  #2  
Old Oct 12, 2014, 11:22 PM
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Travelinglady Travelinglady is offline
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I think many antidepressants can cause mania in people prone to it. So, they are very cautiously given to people like me who have bipolar. However, I am currently taking Wellbutrin, Trazodone, and Cymbalta, in relatively small doses, with no problem.

I can't remember what antidepressant I took 14 years ago that kicked me into mania. It could have been Remeron. I only remember that it caused me to gain a whole lot of weight, so I wouldn't touch it now with a ten-foot celery stick.
Thanks for this!
sideblinded
  #3  
Old Oct 13, 2014, 12:09 AM
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sideblinded sideblinded is offline
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Quote:
Originally Posted by Travelinglady View Post
I think many antidepressants can cause mania in people prone to it. So, they are very cautiously given to people like me who have bipolar. However, I am currently taking Wellbutrin, Trazodone, and Cymbalta, in relatively small doses, with no problem.

I can't remember what antidepressant I took 14 years ago that kicked me into mania. It could have been Remeron. I only remember that it caused me to gain a whole lot of weight, so I wouldn't touch it now with a ten-foot celery stick.
Thanks TL..... My pdoc thought I had bipolar but it only happens when certain AD's kick in. I read somewhere that this occurrence is a type of bipolar....It is not really bipolar in any true sense of the word but there are more types of bipolar than just I and II. Psychiatry is a strange science.

I also have to take small doses of meds. I am actually dreading telling my pdoc that the remeron did this to me. I am afraid he will think it is bipolar. I really don't think that I have bipolar but who knows. I am up late and I don't like to wind down and go to bed. It could just be that I am a night owl as I worked the graveyard shift many years.
  #4  
Old Oct 13, 2014, 02:23 PM
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Only once with my current AD Fetzima. it made me hypomanic for two months. I didn't care as it was better than the severe depression. It wasn't negative mania but not really a euphoric mania either. It went away after two months and Fetzima has been very effective for me.

I am surprised Remeron would cause it.
__________________
The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
Thanks for this!
sideblinded
  #5  
Old Oct 13, 2014, 09:42 PM
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sideblinded sideblinded is offline
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Quote:
Originally Posted by zinco14532323 View Post
Only once with my current AD Fetzima. it made me hypomanic for two months. I didn't care as it was better than the severe depression. It wasn't negative mania but not really a euphoric mania either. It went away after two months and Fetzima has been very effective for me.

I am surprised Remeron would cause it.
Yeah I am surprised that only 30 mg caused it to happen to me. It wasn't euphoric at all. It just sped me up and it had my thoughts going fast. I am not having those issues since I decreased it back to 15mg. In fact I keep forgetting to call and let him know that I had to decrease it back to 15 mg. It is very good at helping me sleep but that is about all.
  #6  
Old Oct 13, 2014, 10:23 PM
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I take 30 for sleep and if works great. I used to take 45 for depression and it didn't work. That was before it was even approved in the US. We had to get an FDA waiver.

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__________________
The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
  #7  
Old Oct 13, 2014, 10:37 PM
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Altered Moment Altered Moment is offline
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Member Since: Feb 2014
Location: Michigan
Posts: 5,481
Wait that's not right. The FDA waiver was for Reboxotine. I don't know whatever happened to that drug.

Sent from my iPhone using Tapatalk
__________________
The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
  #8  
Old Oct 14, 2014, 12:31 AM
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ChipperMonkey ChipperMonkey is offline
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Location: Somewhere/Anywhere/Nowhere
Posts: 1,516
Uhm, you can NOT diagnose most mental illnesses if symptoms were experienced under the influence of drugs, so its complete and total horse hockey to say that experiencing mania while under the influence of psychiatric medication means that you are bipolar!

I experienced psychosis while under the influence of an over the counter medication, and as such could not be diagnosed with anything unless the psychosis returned sans drugs. No more psychosis, ever, so no disorder.

That would be like saying crack cocaine makes you psychotic so you have a mental disorder, even though when you are not on the drug you never experience psychosis. The psychiatric world never ceases to amaze me!
Thanks for this!
AncientMelody
  #9  
Old Oct 14, 2014, 07:46 AM
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Altered Moment Altered Moment is offline
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Member Since: Feb 2014
Location: Michigan
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Actually the DSM V now says if you have AD induced mania you may have a type of bi polar. Like switched mania or something. Something on the low end under bi polar II. I forget. I would have to look it up. Not saying I agree with that just remember reading it.

Sent from my iPhone using Tapatalk
__________________
The "paradox" is only a conflict between reality and your feeling of what reality "ought to be." -- Richard Feynman

Major Depressive Disorder
Anxiety Disorder with some paranoid delusions thrown in for fun.
Recovering Alcoholic and Addict
Possibly on low end of bi polar spectrum...trying to decide.

Male, 50

Fetzima 80mg
Lamictal 100mg
Remeron 30mg for sleep
Klonopin .5mg twice a day, cutting this back
Thanks for this!
sideblinded
  #10  
Old Oct 15, 2014, 10:35 PM
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sideblinded sideblinded is offline
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Member Since: Jul 2014
Location: Iowa
Posts: 5,331
Quote:
Originally Posted by zinco14532323 View Post
Actually the DSM V now says if you have AD induced mania you may have a type of bi polar. Like switched mania or something. Something on the low end under bi polar II. I forget. I would have to look it up. Not saying I agree with that just remember reading it.

Sent from my iPhone using Tapatalk
Zinco, I read the same exact thing. I believe that the DSM V now pinpoints that if an antidepressant induces hypomania that it is classified as on the bipolar spectrum.......I really don't agree with this but I see my pdoc in the am and I bet he diagnoses me with bipolar again! I am so confused with psychiatry.

Older research in this link suggesting putting AD induced mania as bipolar dx in DSM V:

http://psychcentral.com/news/2011/10...der/30300.html

Newer research stating DSM V addition:

http://www.psychiatrictimes.com/bipo...ntidepressants


MDD?

Last edited by sideblinded; Oct 15, 2014 at 10:59 PM.
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