[MoxieDoxie]

As my T suggested it to me. I did order a small bottle to try. I have not gotten it yet.

If you use it what did you feel and what disorder do you have?

ex-T diagnosed me with c-PTSD/Borderline/bulimia

Current T thinks I am along the lines of DID. I still have trepidations about that diagnosis.

[toomanycats]

I take it
It seems to take the edge off my temper when I take it

Similar diagnoses as you

[mcl6136]

Are you at all concerned that your own body produces pain-reducing substances that mediate complex biological processes -- and that supplementing them, via CBD and other substances -- could have serious, unforeseen consequences?

https://en.wikipedia.org/wiki/Endocannabinoid_system

I think anyone who takes these substances under the belief system that they have little or no downside....is simply kidding themselves and conducting an experiment on themselves with an unknown outcome.

Best of luck to you.

[fille_folle]

Well, I just recently got some for my dog (she is almost 19, has arthritis obvi), but the dosage I would have to take would be too expensive. My small bottle was $40, and I'm not wasting it by guzzling it down myself.

[toomanycats]

Originally Posted by mcl6136

Are you at all concerned that your own body produces pain-reducing substances that mediate complex biological processes -- and that supplementing them, via CBD and other substances -- could have serious, unforeseen consequences?

https://en.wikipedia.org/wiki/Endocannabinoid_system

I think anyone who takes these substances under the belief system that they have little or no downside....is simply kidding themselves and conducting an experiment on themselves with an unknown outcome.

Best of luck to you.

That article tells me nothing...
As does your comment.
I am interested but left just...confused

[Patagonia]

Originally Posted by mcl6136

Are you at all concerned that your own body produces pain-reducing substances that mediate complex biological processes -- and that supplementing them, via CBD and other substances -- could have serious, unforeseen consequences?


https://en.wikipedia.org/wiki/Endocannabinoid_system


I think anyone who takes these substances under the belief system that they have little or no downside....is simply kidding themselves and conducting an experiment on themselves with an unknown outcome.


Best of luck to you.

Well according to your citation from Wikipedia , which I’m not a big fan of due to citation issues it does touch on the affiliation of Anandamide.
Interesting....bec this is below is pulled from Wikipedia too.

...”It has been suggested that AM1172 could potentially be developed into a drug that would increase the brain's anandamide levels to help treat anxiety and depression.[28] Black pepper contains an alkaloid, Guineensine, which appears to be a relatively potent Anandamide reuptake inhibitor, thus increasing its physiological effects.”

Maybe this falls into the classic SSRI classification.

[fille_folle]

I do love some black pepper.

[mcl6136]

black pepper aside, I am not a huge WIKI fan, either. Here is a crude explanation:

Your body makes substances called ENDO (inside) cannabinoids on its own. Just like it makes hormones like TSH (thyroid stimulating hormone) and other key ingredients to a balanced metabolism.

Your body's own cannabinoids are essential for well being and pain tolerance/relief.

Supplementing those substances with EXO (from outside your body) cannabinoids like CBD and pot...is a crap shoot, as far as I am concerned, and I would be very careful doing it long term.

Just as I would be very careful taking synthroid (synthetic thyroid drug)on a regular basis if I did not know that I had a thyroid disorder or how much I was taking or any of the side effects. I would also be very careful about supplementing my body with steroid compounds from outside my metabolism...because every day my body synthesizes many of these chemicals on its own.

People who take steroids to bulk up in weightlifting or cheat at cycling can suffer huge consequences down the line. CBD oil may seem like a miracle cure now but I think there are a lot of unanswered questions.

[MoxieDoxie]

Ok so I got it in. No directions on dosing so I went to the website. All it says is start with a low dose but there is nothing saying what a dose is? Is a dose 10 drops or an entire dropper? So I took an full dropper. Yup I feel like I smoked pot with out the "high" part. I don't like how I feel as it mainly in my head and behind my eyes. Not feeling anything in my body. I could not use it if I need to get studying done or work. I think a dropper might have been to much.

[Patagonia]

Sorry I have to disagree.

First, if you are not a big fan of wiki....don’t use it.

Second, meds especially MH meds, are a crap shoot. Just read the warning label of any MH drug that has been thoroughly tested by our own FDA branch & ask the drug companies how much money they spent on bringing that drug to the shelf. Millions??????? And it’s not guaranteed????

Life is a crapshoot. Open the door & see what’s behind it.

[toomanycats]

Originally Posted by MoxieDoxie

Ok so I got it in. No directions on dosing so I went to the website. All it says is start with a low dose but there is nothing saying what a dose is? Is a dose 10 drops or an entire dropper? So I took an full dropper. Yup I feel like I smoked pot with out the "high" part. I don't like how I feel as it mainly in my head and behind my eyes. Not feeling anything in my body. I could not use it if I need to get studying done or work. I think a dropper might have been to much.

All depends on the milligrams in the bottle... it should say somewhere the mg of CBD per dropper or at least per bottle.

The stuff I use is very low -- 1mg per 2 squirts -- but I need a good 10mg+ dose. I need to move to the higher mg per dose stuff but it's expensive and I am cheap heh

[MoxieDoxie]

Originally Posted by toomanycats

All depends on the milligrams in the bottle... it should say somewhere the mg of CBD per dropper or at least per bottle.

The stuff I use is very low -- 1mg per 2 squirts -- but I need a good 10mg+ dose. I need to move to the higher mg per dose stuff but it's expensive and I am cheap heh

The bottle is 500mg. But it does not say a dropper is 500mg so is the entire bottle 500mg or 10 drops 500mg. I am so confused.

I could see how this could be beneficial if I was triggered or in a emotional flashback or if I was waking up at 2 am in the morning with racing thoughts. You could take that at 2am and not have a drug hangover in the morning.

I went to bed at 9pm and did not wake up until 5am so it did something.

[toomanycats]

Originally Posted by MoxieDoxie

The bottle is 500mg. But it does not say a dropper is 500mg so is the entire bottle 500mg or 10 drops 500mg. I am so confused.

I could see how this could be beneficial if I was triggered or in a emotional flashback or if I was waking up at 2 am in the morning with racing thoughts. You could take that at 2am and not have a drug hangover in the morning.

I went to bed at 9pm and did not wake up until 5am so it did something.

If the bottle is 500mg (and, yes, that sounds like the bottle dosage), how many mL is it? You can math out the mg per mL...

If you just want to tell me the brand, I can try to look into it for you

[MoxieDoxie]

Originally Posted by toomanycats

If the bottle is 500mg (and, yes, that sounds like the bottle dosage), how many mL is it? You can math out the mg per mL...

If you just want to tell me the brand, I can try to look into it for you

CBDistillery.com

If I buy a bottle of Fish oil and the front says 1000mg that does not mean I have to take the entire bottle to get 1000mg. One dose is 1000mg and a dose equals 2 capsules. That is how I was perceiving the CBD oil that it is 500mg a dose but I do not know what a dose equals.

[junkDNA]

I've been interested in using CBD as an anti psychotic for a while. however CBD is expensive and it takes large doses to provide benefits for that issue

[toomanycats]

Nope - that's how they get you/market it - you're like "oh wow that sounds so strong" but really that's the strength of the whole bottle -- this is 500mg per 15mL which means 33mg per mL. Unfortunately it's not telling me how many mL are in a dropperful - you could weigh it to get some idea though.

[mcl6136]

Originally Posted by Patagonia

Sorry I have to disagree.

First, if you are not a big fan of wiki....don’t use it.

Second, meds especially MH meds, are a crap shoot. Just read the warning label of any MH drug that has been thoroughly tested by our own FDA branch & ask the drug companies how much money they spent on bringing that drug to the shelf. Millions??????? And it’s not guaranteed????

Life is a crapshoot. Open the door & see what’s behind it.

And if you are not a fan of mental health drugs, don't use them either.

[mostlylurking]

I've used CBD and as TMC says, the total milligrams refers to the whole bottle. I also found it confusing. It takes a bit of math to figure out dosages in drops, but then, I don't think there are clear guidelines about dosages for mental health purposes yet. The half-life of CBD is a few or several days, so, when you start using it you're kind of building up your levels for the first week, maybe. So, to give it a fair trial you might choose a dose that seems affordable and stick with it for a week or two before deciding if it seems helpful.

When I've used it (about 10 drops a day of what I suspect is a similar concentration to yours) I noticed very little effect for the first few days, but I eventually slept better, and felt appropriately tired and sleepy when I should have been tired (instead of being keyed up or wired late at night). It may have helped a bit with anxiety too, though not as much as other things I've taken (valerian root, chamomile).

[toomanycats]

I switched things up.
I use Plus CBD Oil -- was using the Green line, the 1mg per 2 squirts.
Swapped to the Gold line, the 15mg capsules.
I definitely like these 15mg capsules. Too bad they are ridiculously expensive....

[MoxieDoxie]

Oh you are suppose to take it everyday? I thought it was use it as you thought you might need it.

[mostlylurking]

I think you can use it as needed too -- I guess it depends on what you're using it for? My first awareness of CBD was that a friend gave it to her son to prevent seizures (which it was entirely effective at for 5+ years) and in that case they needed to keep it in his system at a somewhat constant level. For me, I was interested in sleeping better, so it wasn't an "as needed" situation exactly -- I don't always know when I'll have trouble sleeping. I also wanted it in my system regularly to see how it affected my sleep.

As medications go CBD and marijuana are very safe so I would just experiment, because everyone's system is different! But if your T suggested it as needed then never mind what I said about half life and all that.