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  #1  
Old Feb 23, 2012, 08:58 PM
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Does anyone have experience with fish oil causing sleep issues?

I added 1290mg of fish oil about 10 days ago. It really helped lift the foggy brain feeling, but now I've noticed my sleep pattern is all out of whack. I am sleeping 4 or 5 hours when I usually need at least 7 or 8.

I started using light therapy in the mornings about a month ago and I take a Vitamin D3 supplement. We were trying that out to see if it helped with depressive symptoms.

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  #2  
Old Feb 24, 2012, 06:16 PM
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I take fish oil and have insomnia but I don't know if there is a correlation. Have you tried not taking the fish oil to see if your sleep improves?
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Old Feb 24, 2012, 08:45 PM
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I forgot to take it this morning...not on purpose. I was rushed and it slipped my mind. We'll see how sleep goes tonight.
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Old Feb 24, 2012, 10:30 PM
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Hope you and I get some good sleep tonight.
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Old Mar 05, 2012, 10:10 PM
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I'm interested to see how this goes. I have been taking fish oil for several years & have sleep issues. But the sleep issues are newer than the fish oil. I take it right before I go to bed.
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Old Mar 05, 2012, 10:36 PM
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My t told me to stop taking the fish oil when I had racing thoughts. The insomnia did go away, but I also stopped my light therapy at the same time (I was down and not being too good about self-care). Now I am beginning to wonder if the racing thoughts actually came from too much light therapy. I took a 4 day break from light therapy and when I started back up the racing thoughts were back stronger than before. I see her on Thurs and am hoping we can give the fish oil another try.
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Old Mar 10, 2012, 06:26 PM
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Did you reintroduce the fish oil?
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Old Mar 10, 2012, 06:55 PM
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My session didn't really go as I hoped and I never got a chance to ask about it. So rather than upset the apple cart more than I think I already did in my session, I am waiting until I see her in two weeks to ask.
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  #9  
Old Mar 18, 2012, 02:28 AM
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Fish may have earned its reputation as “brain food” because some people eat fish to help with depression, psychosis, attention deficit-hyperactivity disorder (ADHD), Alzheimer’s disease, and other thinking disorders. [http://www.webmd.com/vitamins-supple...ame=FISH%20OIL]

O_O Does this help?
  #10  
Old Apr 12, 2012, 01:19 PM
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I'm having the same issue. I've been taking quite a bit of fish oil, as well as seriously increasing the amount of fish I eat for the last two weeks. I have had insomnia coming on for almost a week, getting increasingly worse until the night before last when I woke at 2 am and couldn't get back to sleep.

Last night I didn't take any and slept like a rock. I did take some in the morning yesterday.

I googled it and apparently some people get insomnia and anxiety with fish oil. I'm going to continue taking a small amount in the morning for a while longer, but my long-term goal is to get the omega 3's from my diet - fish, leafy greens, flax seed, etc. - and decrease the omega 6's I'm consuming.
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  #11  
Old Apr 12, 2012, 01:23 PM
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have you tried counting fish to get back to sleep
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  #12  
Old Apr 12, 2012, 01:45 PM
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Quote:
Originally Posted by Aslan View Post
have you tried counting fish to get back to sleep
I haven't, but it's amusing to me that I've taken up swimming at about the same time I started eating lots of fish. It's like first I invade their world, then I start eating them.
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  #13  
Old Apr 28, 2012, 10:04 AM
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I ran across something interesting while trying to research fish oil. It kind of got me speculating. This is just a hypothesis of mine based on the following information.

Apparently fish oil oxidizes easily. They know this from measuring an organic compound called malondialdehyde in the urine of people taking fish oil. The fix is an antioxidant, vitamin E.

Quote:
Fish oil and vitamin E go together
BELTSVILLE, MARYLAND. Fish oils are beneficial in the prevention of cancer and cardiovascular disease. They do, however, oxidize very easily and therefore add to the oxidant stress on the body. An experiment was recently carried out by the U.S. Department of Agriculture to see if an increased intake of vitamin E could counteract this detrimental effect of fish oils. Forty men aged 32 to 44 were involved. The men consumed a controlled diet for a total of 28 weeks. For the first 10 weeks they received placebo oil capsules (15 g/day), for the next 10 weeks they received fish oil capsules (15 g/day), and for the last 8 weeks they received the fish oil plus 200 mg of vitamin E (all-rac-alpha-tocopherol). The urinary excretion of peroxidation products (malondialdehyde) more than doubled when the fish oil capsules were introduced but then dropped by a factor of four when vitamin E was added. The vitamin E concentration in the red blood cells dropped very significantly when fish oil was ingested but more than recovered with the vitamin E supplement. It is concluded that the negative effects of fish oil consumption can be overcome by taking them together with vitamin E.
Nair, Padmanabhan P., et al. Dietary fish oil-induced changes in the distribution of alpha-tocopherol, retinol, and beta-carotene in plasma, red blood cells, and platelets: modulation by vitamin E. American Journal of Clinical Nutrition, Vol. 58, July 1993, pp. 98-102

http://www.oilofpisces.com/vitamine.html
At least one study correlates insomnia with malondialdehyde (and other signs of oxidative stress). These researchers seem to conclude that the lack of sleep is leading to oxidative stress. But what if it's the reverse: increased oxidative stress is leading to sleep problems? That would explain why fish oil capsules were causing me insomnia.

Maybe when people get their fish oil from diet (i.e., they eat fish) rather than taking capsules, they're less likely to have this sleep issue because they're getting other necessary nutrients (antioxidants) from the rest of the fish and from other foods they're eating with the fish. Another reason taking supplements isn't an adequate substitute for a healthy diet?

I may get some vitamin E and test my theory.

Quote:
Oxidative stress in patients with primary insomnia.

Gulec M, Ozkol H, Selvi Y, Tuluce Y, Aydin A, Besiroglu L, Ozdemir PG.
Source

Department of Psychiatry, Faculty of Medicine, Ataturk University, Erzurum, Turkey.

Abstract

OBJECTIVE:
Many physiological and pathological processes, such as infections, environmental toxins, and ionizing radiation increase bodily concentrations of oxidizing substances, known as free radicals, which lead to neurodegenerative disorders. Sleep is one of the most important factors contributing to health; however, insomnia is among the most prevalent health complaints.

METHODS:
In this study, for the first time in the literature, we investigated the effects of primary insomnia on certain oxidative stress biomarkers. For this purpose, glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and myeloperoxidase (MPO) activities and levels of reduced glutathione (GSH) and malondialdehyde (MDA) were measured in 30 patients with primary insomnia and 30 healthy volunteers

RESULTS:
Our results show that the patients with primary insomnia had significantly lower GSH-Px activity and higher MDA levels compared with the controls.

CONCLUSION:
These results may indicate the important role of sleep in attenuating oxidative stress.

http://www.ncbi.nlm.nih.gov/pubmed/22401887
BTW, malondialdehyde also seems to be associated with other neuropsychiatric nasties - like the negative symptoms of sz. Maybe this is why my son seems to have gotten worse rather than better since starting fish oil? (You'll have to follow the link to the study and check out the Mesh headings to see the mention of malondialdehyde. It's not mentioned in the abstract.)

Quote:
Elevated plasma lipid peroxides at the onset of nonaffective psychosis.

Mahadik SP, Mukherjee S, Scheffer R, Correnti EE, Mahadik JS.
Source

Department of Psychiatry, Medical College of Georgia, Augusta, USA.

Abstract

BACKGROUND:
Impaired antioxidant defense and increased lipid peroxidation has been reported in chronic schizophrenic patients. Recently, we have reported an impaired antioxidant defense in never medicated first-episode schizophrenic and schizophreniform patients. We report now a concomitant increase in plasma lipid peroxides.

METHODS:
The plasma lipid peroxides [thiobarbituric acid reactive substances (TBARS)] were analyzed by chemical and high performance liquid chromatography procedures in 26 patients admitted for a first episode of schizophrenic (N = 17) or schizophreniform psychosis (N = 9) and 16 normal control subjects. The patients had a duration of 4.5 days (SD 2.8) of psychosis at the time of the study.

RESULTS:
Plasma TBARS levels were significantly higher in the patients than in normal controls (P < .002). TBARS levels were above the normal range in 16 of the 26 patients. Higher TBARS levels were associated with a greater severity of negative symptoms and lower red blood cell activity of the glutathione peroxidase.

CONCLUSIONS:
The findings indicate ongoing oxidative injury at the very onset of psychosis. If valid, this would indicate the need for adjunctive antioxidant treatment from the beginning of the course of nonaffective psychoses. This might prevent a deteriorating course and development of the deficit syndrome.

http://www.ncbi.nlm.nih.gov/pubmed/9583001
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  #14  
Old Apr 28, 2012, 04:02 PM
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I was under the assumption that supplemental Vitamin E wasn't exactly good for you. Am I way off base here?

But if supplemental Vitamin E is indeed okay then I just might look into it as well to see if it also helps with insomnia because I'm still experiencing it on Ambien CR and 6mg of melatonin. My issue with insomnia is not with falling asleep but with waking up real early after being in bed only 4 or 5 hours. Once I wake up, trying to get back to sleep is futile.

Costello, keep us posted of your Vitamin E experiment. When do you think you'll start? Wishing you loads of luck!
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Old Apr 29, 2012, 07:09 PM
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I'll start taking vitamin E tonight. We'll see if it helps. I started my son taking five antioxidants last night because he's decompensating. Doesn't seem to be helping him - but his problems are more serious that insomnia, I'm afraid.
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  #16  
Old May 07, 2012, 09:26 AM
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Originally Posted by cybermember View Post
Costello, keep us posted of your Vitamin E experiment. When do you think you'll start? Wishing you loads of luck!
I've been taking 800 IU of vitamin E along with the fish oil for a bit over a week now. I haven't had insomnia during that time, but I've also been taking the fish oil in the morning rather than the night, so I'm not sure what's making the difference.
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  #17  
Old May 07, 2012, 10:12 AM
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I'm glad you're sleeping better.

I guess to see which is doing what I would eliminate the vitamin E for at least a week, being that it's a fat soluble vitamin, to see if your insomnia returns. It could be that by taking fish oil (another fat soluble vitamin) in the morning is early enough not to cause insomnia. But if by a weeks time your insomnia kicks back in then reintroduce vitamin E to see if that takes care of it. By then you should know which is doing what.

Keep us posted!
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  #18  
Old May 08, 2012, 08:03 AM
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Ugh! Slept badly last night, but don't think it was insomnia per se.

Woke at 2 - I think because my son had left on a light which was shining into my bedroom. I got up to turn it off, and I probably would have been able to get back into bed and go right back to sleep, but I found that my son was wide awake and hadn't been able to get to sleep at all that night. Not feeling sleepy at all. That worried me because his episodes often start with severe persistent insomnia. So I sat up with him for an hour or so. I was able to get back to sleep fairly easily once I returned to bed.

Not sure if that was insomnia or not. I think not. Even though I didn't feel sleepy while I was talking to my son - wide awake, in fact - I was woken by something in my environment and I could get back to sleep when I wanted to.

I'm becoming increasingly convinced that taking an antioxidant with fish oil is a good idea - even if you don't have insomnia. I just read this morning, for example, that fish oil consumption tends to lower vitamin E levels for some unknown reason. Possibly it's depleted because of the need to deal with oxidative stress from the fatty acid peroxidation?
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Old May 08, 2012, 04:55 PM
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Costello, how much fish oil as well as vitamin E are you taking?

I take 2,126mg of molecularly distilled fish oil (EPA 800mg; DHA 400mg). I'm thinking if vitamin E ends up working for you perhaps it could work for me too, but I don't know of a dosage to start. I've found that getting 9 hours of sleep is optimal for me but for the most part I don't always get that, but somewhere between 5-8 hours a night. BTW, I'm no longer relying on melatonin to maintain my sleep but just to take it prophylactically being that melatonin declines with age (I'm 49). Initially, it seemed to have worked but have come to the conclusion that it was just a placebo effect so I'm back to square one with looking for ways of getting a good night's sleep. The other option for me (which I'm not too keen on) is increasing my antipsychotic. I believe I'm fairly stable - just that my sleep really sucks.
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Old May 09, 2012, 06:50 AM
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Costello, how much fish oil as well as vitamin E are you taking?
I'm glad you asked. I went to get the exact numbers off the bottle for you, and I see that my son bought the wrong thing this time. He got a combo fish oil and vitamin D which includes a much lower dose of EPA/DHA than the other one I was using. His pdoc wanted him to take at least 1000 mg EPA. The product I was buying had something like 1200 mg to 1400 mg EPA (plus DHA too, but I can't even ballpark that number for you). The product my son picked up has 720 mg total of both EPA and DHA (no breakdown given on how much of each). That second product is the one I've been taking with this vitamin E experiment.

This pretty much throws my experiment out the window. I'll buy the other product today and try again to see what happens.

Back to the drawing board!
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Old May 09, 2012, 08:00 PM
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The fish oil that you'd be taking, is it 1200-1400mg of EPA and DHA combined or is it just for EPA alone? I'm wondering if I can get higher EPA and DHA than I'm already getting.
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Old May 10, 2012, 10:05 AM
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Originally Posted by cybermember View Post
The fish oil that you'd be taking, is it 1200-1400mg of EPA and DHA combined or is it just for EPA alone? I'm wondering if I can get higher EPA and DHA than I'm already getting.
That was the number for the EPA alone. Since the pdoc was insistant that it contain at least 1000 mg of EPA, I focused on that number only.

I could find that kind at the store yesterday, so I picked up a different kind. The new kind - which I started taking yesterday evening - has about 1300 mgs of EPA in two capsules. (I forgot to check the DHA again. Darn it! I'll let you know about the DHA when I get a chance to check it.)

I'm thinking that if it's going to cause me insomnia, it'll be at least a week or so.
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Old May 10, 2012, 10:12 AM
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I've found that getting 9 hours of sleep is optimal for me but for the most part I don't always get that, but somewhere between 5-8 hours a night.
Me too. But the best I can hope for right now is 7 hours. I have to get up at 5 am for work. And I like to spend some time hanging out with my son in the evening, so I'm not usually asleep until 10 pm.

Quote:
BTW, I'm no longer relying on melatonin to maintain my sleep but just to take it prophylactically being that melatonin declines with age (I'm 49). Initially, it seemed to have worked but have come to the conclusion that it was just a placebo effect so I'm back to square one with looking for ways of getting a good night's sleep. The other option for me (which I'm not too keen on) is increasing my antipsychotic. I believe I'm fairly stable - just that my sleep really sucks.
A low-carb diet cured my lifelong insomnia. I don't know if reducing sugar and/or processed carbs might help you?

I'm a bit obsessive about turning off all lights at night and having it as dark as I can possibly get - partly because I can't sleep with lights on, but partly because light suppresses melatonin production. Do you keep your room dark at night? I even cover the face of my clock radio and the little light on my tv converter box.
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Old May 10, 2012, 07:41 PM
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EPA = 647 x 2 = 1294 mg
DHA = 278 x 2 = 556 mg
Vitamin E = 800 IU

night 2

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  #25  
Old May 10, 2012, 07:43 PM
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My room is pretty much dark except for the light on the cable box but it doesn't interfere with me going to sleep. Actually, I view it as a night light. In addition to my dark room I sleep with two sound machines and the whirring of a small fan. I am an extremely light sleeper so they really help mask any noise (people, thunderstorms, etc.) that might occur outside of my room.

I'm not a big carb eater as too many carbs make me not feel well but I do eat carbs in moderation alongside some protein and/or veggies and fruits. For the most part I stay away from sugar and processed foods but every so often I'll eat a couple of cookies. I love cookies but again, not too many. So for me, carbs and processed foods are not a factor in affecting my sleep. I wish I knew what is causing my insomnia as this morning I was up at 5:30am after going to bed at 11:30pm. Who knows.

What is the name brand of the fish oil that you are taking that has a high EPA?
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