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#1
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Well, this is the first time in a long time that I am trying a new medication... rexulti for bipolar depression. I am treatment resistant and have never responded well to antidepressants and am not taking anything at the moment although if rexulti by itself doesn't help I'll ask my pdoc if he will try me on an antidepressant again...
I stepped up from 0.5 to 1 mg a few days ago. Today felt pretty spacey in the middle of the day. Still taking a low dose of olanzapine but will get off that when I step up to 2 mg of rexulti. Olanzapine raises by blood sugar into prediabetes range but when i got off it last time, my blood sugar fell into normal range... I am not having psychotic symptoms so that is good although my doom and gloom depressions are a kind of mild psychosis too; they just aren't seen that way by medical people because the thoughts are not that unusual in the sense that many depressed people have them and they are not grandiose and paranoid. Please share if you have had experience with rexulti. I am hoping this medication will give me a bit of a lift without making me manic.
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BP 1 with psychotic features 50 mg Lyrica 50 mcg Synthroid 2.5 mg olanzapine |
#2
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Rexulti is the new and some say improved abilify. Chances are if you have taken and tolerated abilify rexulti will be a good drug for you.
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Guiness187055 Moderator Community support team |
![]() Sunflower123
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![]() tecomsin
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#3
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I’ve been on rexulti for I guess about a month now. I have been slowly coming out of severe depression. Not sure if the rexulti has anything to do with it or if it’s just my natural cycle. If it is the rexulti I would say give it Time as I literally JUST started feeling better a couple of days ago. I am having increased hunger and compulsive eating but that could be the depakote. In the very beginning taking it I was completely exhausted but that side effect went away after about a week.
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Of course it is happening inside your head. But why on earth should that mean that it is not real? -Albus Dumbledore That’s life. If nothing else, that is life. It’s real. Sometimes it f—-ing hurts. But it’s sort of all we have. -Garden State |
![]() 99fairies, Sunflower123
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![]() 99fairies, tecomsin
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#4
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Thanks for the info Guiness. I did try abilify years ago but probably didn't stick with it long enough... in any case I don't remember it having an effect one way or the other. I want to get of Zyprexa now because of what it does to my glucose levels and my insurance covers it so why not try the latest drug which hopefully has fewest side effects.
How are you doing with rexulti now wildflowerchild? I was also dead tired the first week, then had a headache for a few days and now am back to my normal low energy depressive state. I've cut down on zyprexa to 1.25 and the plan is to go off it completely when I get to 2 mg of rexulti in a few days. So far I am not having any delusions or hallucinations.
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BP 1 with psychotic features 50 mg Lyrica 50 mcg Synthroid 2.5 mg olanzapine |
#5
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I'm allergic to abilify but tried rexulti. I'm not sure how much it helped because I had my first psychotic episode while on it.
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schizoaffective bipolar type PTSD generalized anxiety d/o haldol, prazosin, risperdal and prn klonopin and helpful cogentin |
![]() still_crazy, tecomsin
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![]() still_crazy
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#6
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Quote:
I’m doing much better. Mood is almost at a baseline level, no depression. I did run out on Tuesday and couldn’t get more till Friday (insurance being idiots) and started terrible withdrawal so just keep that in mind. Try not to run out and if you choose to stop you’ll need to taper. I’m still struggling with compulsive eating but that’s probably due to depakote, although I’ve read rexulti can cause weight gain as well. I’m lowering depakote so we will see if that helps the weight gain.
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Of course it is happening inside your head. But why on earth should that mean that it is not real? -Albus Dumbledore That’s life. If nothing else, that is life. It’s real. Sometimes it f—-ing hurts. But it’s sort of all we have. -Garden State |
![]() tecomsin
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#7
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well I didn't get out yesterday with a sore throat, a driveway full of snow, and -30 C plus windchill outside... I didn't get out to pick up rexulti and I have one pill left so will take it this evening instead of the morning. Hopefully that will get me through Monday without a pill and I pick up my prescription Tuesday morning.
Rexulti is messing a bit with my digestive system. Lots of gas and some constipation but so far it is tolerable.
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BP 1 with psychotic features 50 mg Lyrica 50 mcg Synthroid 2.5 mg olanzapine |
#8
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I'm on it; it's fine. Insurance won't cover it, though, so I'm stuck using samples.
I don't have an insatiable hunger on it, nor have I gained weight. In fact, I can't think of any side effects at all, except maybe a little constipation, but that's a hell of a lot better than the Seroquel side effects I had prior to that. Seroquel was a nightmare. |
![]() still_crazy
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![]() still_crazy
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#9
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well my anxiety peaked today repeatedly so I took 1.25 mg olanzapine. I usually would want to wait till the evening but it was getting out of hand. If I have to take rexulti and olanzapine I might as well just take olanzapine. They are both antipsychotics. Well I will take another month of the rexulti and evaluate then to give it time. Maybe today is just a bad day. Tomorrow is my probation meeting. It warmed up over 22 C in one day today from the low at night. It has been brutally cold in Canada. I have thoughts of going into assisted living if they will take away my license and that may be the best course for everyone at that point.
I've reasons to be anxious but alas no real reason. my anxiety has outlived any given situation. this bipolar disorder or schizoaffective, whatever it is, is not something I had hoped all my life to get, or 'deserved' for any moral failings I did always live my life according to a certain degree of common sense but lately that had failed me and I broke the law in my psychosis... so it is reasonable to be sure that won't happen again. i'll just park myself at the hospital. it is better than jail.
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BP 1 with psychotic features 50 mg Lyrica 50 mcg Synthroid 2.5 mg olanzapine |
![]() still_crazy
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![]() still_crazy
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#10
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Quote:
Quote:
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BP 1 with psychotic features 50 mg Lyrica 50 mcg Synthroid 2.5 mg olanzapine |
#11
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communication with my son can be extremely activating. he's travelling the world after graduating and having what sounds like a good time staying in hostels and getting to know and travel with other people. he's in nice warm places instead of stuck at -30C...
so he texted me last night that he has only one card to get money from and that card has stopped working... so what am i supposed to do about it. i worry about him anyway and i'm a worrier and that added stress bumped me over my ability to sleep threshold so i had to take an olanzapine and lyrica to fall back asleep. he turns my worry machine up a few notches. i heard those rapid texts in the middle of the night and new it was him and wasn't good news. otherwise i rarely hear from him except a few times he sends some photos and stories of his travels. so the rexulti at 2 mg a day is not enough. i'll have to talk to my pdoc next week about all this.
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BP 1 with psychotic features 50 mg Lyrica 50 mcg Synthroid 2.5 mg olanzapine |
![]() Anonymous45023
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